Method for treatment of glutamate related disorders

A - Human Necessities – 61 – K

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A61K 31/27 (2006.01) C07C 333/02 (2006.01)

Patent

CA 2269838

A method of using a compound of formula (I) wherein R1, R2, R3, X and n have any of the meanings defined in the specification, to antagonize glutamate binding, or to treat glutamate-related disorders is provided. Novel compounds, intermediates and pharmaceutical compositions are also provided.

Le procédé faisant l'objet de cette invention permet d'utiliser un composé représenté par la formule (I), dans laquelle R?1¿, R?2¿, R?3¿, X et n ont n'importe lesquelles des significations définies dans la description de l'invention, pour s'opposer par effet antagoniste à la fixation du glutamate ou pour traiter les troubles liés au glutamate. De nouveaux composés, de nouveaux intermédiaires et de nouvelles compositions pharmaceutiques sont également présentés.

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