G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/00 (2006.01) C07K 14/47 (2006.01) C07K 14/665 (2006.01)
Patent
CA 2422068
Disclosed is a method to identify compounds useful for reducing insulin resistance is a patient, and particularly a patient that has insulin resistance associated with obesity and/or type II diabetes. Also disclosed is a method of reducing insulin resistance in a patient by administering a compound identified using the method of the invention, and particularly, by administering an antagonist of melanocortin stimulating hormone (MSH) biological activity.
L'invention porte sur un procédé d'identification de composés réduisant la résistance à l'insuline chez un patient, et en particulier chez un patient chez qui la résistance à l'insuline est associée à l'obésité ou au diabète de type II. L'invention porte également sur un procédé réduisant la résistance à l'insuline chez un patient par administration d'un composé identifié à l'aide du procédé de l'invention, et en particulier par administration d'un antagoniste de l'activité biologique de la mélanocortinestimuline (MSH).
Brennan Miles B.
Hochgeschwender Ute
Eleanor Roosevelt Institute
Goodwin Mckay
Oklahoma Medical Research Foundation
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