Method for treatment of tumors using combination therapy

Details Method for treatment of tumors using combination therapy Method for treatment of tumors using combination therapy

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 38/18 (2006.01) A61K 38/20 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2426659

An improved method for treatment of a tumor bearing subject comprising administering to said subject a combination of from two to five agents is disclosed. The agents may be agents that mobilize dendritic cells, agents that cause apoptosis and/or necrosis of tumor cells, chemoattractants, agents that stimulate maturation of dendritic cells, and agents that enhance an anti-tumor response of a T cell.

L'invention concerne un procédé amélioré de traitement d'un patient porteur de tumeur, qui consiste à lui administrer une combinaison d'au moins deux agents. Il peut s'agir d'agents qui mobilisent des cellules dendritiques, d'agents qui provoquent l'apoptose et/ou la nécrose de cellules tumorales, de facteurs chimiotactiques, d'agents qui stimulent la maturation des cellules dendritiques et d'agents qui renforcent la réponse antitumorale d'un lymphocyte T.

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