C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/06 (2006.01) C07K 14/605 (2006.01) C12N 9/52 (2006.01)
Patent
CA 2485695
The invention provides methods for making peptides from a polypeptide containing at least one copy of the peptide using clostripain to excise the peptide from the polypeptide. The methods enable the use of a single, highly efficient enzymatic cleavage to produce any desired peptide sequence.
L'invention concerne des méthodes d'obtention de peptides à partir d'un polypeptide renfermant au moins une copie du peptide, consistant à exciser le peptide du polypeptide à l'aide clostripaïne. Ces méthodes permettent d'obtenir n'importe quelle séquence peptidique à l'aide d'un seul clivage enzymatique de grande efficacité.
Bossard Mary J.
Holmquist Barton
Luan Peng
Merrifield Edwin H.
Seog Seo Jin
Gowling Lafleur Henderson Llp
Medtronic Inc.
Restoragen Inc.
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