C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2647277
The present invention provides for a method of using BOC/CDO hedgehog antagonists to inhibit hedgehog signaling, as well as treating and diagnosing disorders relating to hedgehog signaling or overexpression of hedgehog, including cancer, cell proliferative disorders, and angiogenesis, neurological disorders, as well as other conditions affected by hedgehog signaling such as hair growth, neural stem cell differentiation, chondrogenesis and osteogenesis, lung surfactant production, formation of lamellated bodies in lung cells.
L'invention porte sur une méthode utilisant les antagonistes BOC/CDO du hedgehog pour inhiber l'émission des signaux du hedgehog et traiter et diagnostiquer par là les troubles liés à cette émission et à la surexpression du hedgehog, dont le cancer, les troubles liés à la prolifération cellulaire et l'angiogenèse, les troubles neurologiques, et d'autres états affectés par cette émission tels que la croissance capillaire, la différenciation des cellules souches neurales, la chondrogenèse et l'ostéogenèse, la production de tensioactifs pulmonaires et la formation de corps lamellés dans les cellules des poumons.
de Sauvage Frederic J.
Tian Hua
Genentech Inc.
Smart & Biggar
LandOfFree
Method for using boc/cdo to modulate hedgehog signaling does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for using boc/cdo to modulate hedgehog signaling, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for using boc/cdo to modulate hedgehog signaling will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1766825