Method of administering amiloride

Details Method of administering amiloride Method of administering amiloride

A - Human Necessities

61

K

A61K 9/72 (2006.01) A61K 31/495 (2006.01) A61M 15/00 (2006.01)

Patent

CA 2093233

2093233 9205779 PCTABS00011 Disclosed is a method of removing retained mucus secretions from the lungs of a subject in need of such treatment. The method comprises delivering by inhalation an aerosol suspension of respirable solid particulate amiloride to the respiratory system of the subject. As a result of the treatment, the secretions are hydrated and more easily transported from the lung via mucociliary action. Pharmaceutical compositions comprised of solid particulate amiloride are also disclosed.

Est décrite une méthode d'élimination des sécrétions muqueuses qui s'accumulent dans les poumons d'un sujet ayant besoin d'un tel traitement. La méthode consiste à administrer par inhalation, dans l'appareil respiratoire du sujet, une suspension aérosol d'amiloride particulaire solide inhalable. € la suite du traitement, les sécrétions sont hydratées et sont plus facilement repoussées hors du poumon par la fonction mucocillaire. Sont également décrites des compositions pharmaceutiques composées d'amiloride particulaire solide.

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