Method of asymmetrically reducing...

Details Method of asymmetrically reducing... Method of asymmetrically reducing...

C - Chemistry, Metallurgy

07

D

C07D 233/60 (2006.01) C07B 53/00 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2556075

A process for producing an optically active 4-[hydroxy[5-(imidazol-1-yl)-2- methylphenyl]methyl]3,5~dimethylbenzoic acid or an ester thereof, characterized by reacting 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- di~methylbenzoic acid or an ester thereof with a silane agent in the presence of a specific zinc compound and an optically active diamine compound.

Procédé pour la production d'un acide ou ester d'acide optiquement actif de 4-[hydroxy[5-(imidazol-1-yl)-2-methylphenyl]méthyle]3,5­diméthylbenzoique caractérisé par la réaction de l'acide ou l'ester d'acide de 4-[5-(imidazol-1-yl)-2-méthylbenzoyl]-3,5-di­méthylbenzoique avec un agent silane en présence d'un composé de zinc spécifique et un composé de diamine actif optiquement

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