Method of automatically detecting agglutination reaction and...

G - Physics – 01 – N

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G01N 33/82 (2006.01) G01N 21/82 (2006.01) G01N 33/53 (2006.01)

Patent

CA 1269324

ABSTRACT OF THE DISCLOSURE The invention provides a method of assaying an antigen or antibody in a sample by bringing the antigen - or antibody-containing sample into contact with a support for agglutination reaction as sensitized with an antibody or antigen respectively corresponding to the antigen or antibody in said sample and determining the quantity of the resulting agglutinate precipitate, which comprises measuring the diameter of the precipitate by means of a one-dimensional image sensor capable of sensing, on a line passing the center of said agglutinate precipitate, the intensity of the light from a light source after its passage through the agglutinate precipitate, and an apparatus for assaying an antigen or antibody in a sample by the above method. The method and apparatus provided by the invention make it possible to determine the agglutinate quantity objectively and quickly and are very useful in automatically detecting agglutination reactions in the field of diagnostic apparatus.

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