Method of bowel cleansing

Details Method of bowel cleansing Method of bowel cleansing

A - Human Necessities

61

K

A61K 31/4402 (2006.01) A61K 31/765 (2006.01)

Patent

CA 2569178

Stimulant laxative in combination with an osmotic laxative produces safe and ef~fective bowel and colon cleansing with a reduced volume of liquid input. Administering to a patient an oral stimulant laxative, such as bisacodyl, followed, after a biologically determined interval, by a reduced volume of a PEG in water solution cleanses the bowels and colon in preparation for diagnostic colonoscopy, without the profuse uncontrollable diarrhea that typically follows either ingestion of large volume isotonic lavages, or smaller volume hypertonic lavages.

Selon l'invention, un laxatif stimulant associé à un laxatif osmotique permet un nettoyage sûr et efficace de l'intestin et du côlon, le volume de liquide entrant étant également réduit. L'administration à un patient d'un laxatif stimulant oral, tel que le bisacodyle, suivie par l'administration, après un intervalle déterminé biologiquement, d'un volume réduit de polyéthylèneglycol dans une solution aqueuse permet le nettoyage des intestins et du côlon en préparation d'une côlonoscopie diagnostique. Cette méthode permet d'éviter une diarrhée profuse incontrôlable généralement entraînée par l'ingestion d'un volume important de lavages isotoniques ou d'un volume moins important de lavages hypertoniques.

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