Method of cancer therapy

Details Method of cancer therapy Method of cancer therapy

A - Human Necessities

61

K

A61K 31/404 (2006.01) A61K 31/337 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2435921

Disclosed is a process of treating a patient suffering from cancer. The process compriese administering to a patient over a period of up to about 15 days a first component and a second component. The first component consists of a pharmaceutical composition containin as an active ingreadient a compound of formula (I) or a pharmaceutically acceptable salt or ester of said compound. the second ocmponenet consists of a n injection solution containing as an active ingredient paclitaxel. The amount of each componet in the combination is such that the combination is therapeutically effective. The components are administered concomitantly or sequentially ina three week to four week treatment cycle for as long as the tumor remains under control and the patient tolerates the regimen.

Cette invention se rapporte à une méthode de traitement d'un patient atteint d'un cancer. Cette méthode consiste à administrer à un patient, sur une durée pouvant atteindre quinze jours, un premier et un second composant. Le premier composant renferme une composition pharmaceutique contenant, comme ingrédient actif, un composé de la formule (I) ou un sel ou un ester pharmaceutiquement acceptable dudit composant. Le second composant renferme une solution d'injection contenant, comme ingrédient actif, du paclitaxel. Les composants contenus dans la combinaison sont présents en quantité suffisante pour assurer à ladite combinaison une efficacité thérapeutique. Lesdits composants sont administrés au patient de manière concomitante ou séquentielle au cours d'un cycle de traitement de trois ou de quatre semaines, tant que la tumeur reste sous contrôle et que le patient tolère le régime posologique.

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