A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4184 (2006.01) A61P 35/00 (2006.01) A61K 31/60 (2006.01) A61P 35/04 (2006.01)
Patent
CA 2380414
Methods of treating and inhibiting cancer in animals by administering a therapeutically effective amount of a pharmaceutical composition having benzimidazole of general formula (I), wherein X is hydrogen, halogen, alkyl of less than 7 carbon atoms or alkoxy of less than 7 carbon atoms; n is a positive integer of less than 4; Y is hydrogen, chlorine, oxychloro, nitro, methyl or ethyl; and R is hydrogen, or an alkyl group of from 1 to 8 carbon atoms and R2 is NHCOOR1 wherein R1 is aliphatic hydrocarbon of less than 7 carbon atoms, and preferably an alkyl group of less than 7 carbon atoms and pharmaceutically acceptable derivatives alone, or in combination, or in conjuction with other therapeutic agents such as other cancer inhibiting compounds, and operative combinations thereof.
La présente invention concerne un traitement curatif et préventif du cancer chez des animaux. En l'occurrence, on administre une quantité thérapeutiquement suffisante d'une composition pharmaceutique comportant un benzimidazole représenté par la formule générale (I), ou certains de ces dérivés pharmaceutiquement admis, seuls ou en combinaison ou en conjonction avec d'autres agents thérapeutiques tels que d'autres composés anticancéreux, et certains de leurs combinaisons fonctionnelles. Dans cette formule, X est hydrogène, halogène, C1-C6 alkyle ou C1-C6 alcoxy; n est un entier positif de 1 à 3; Y est hydrogène, chlore, oxychloro, nitro, méthyle ou éthyle; et enfin, R est hydrogène, ou groupe C1-C7 alkyle, R2 étant NHCOOR1, auquel cas R1 est C1-C6 hydrocarbure aliphatique, et de préférence un groupe C1-C6 alkyle.
Mbm Intellectual Property Law Llp
The Procter & Gamble Company
Uaf Technologies And Research Llc
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