Method of chlorination

Details Method of chlorination Method of chlorination

C - Chemistry, Metallurgy

07

D

260/297.3

C07D 213/803 (2006.01) C07D 213/80 (2006.01)

Patent

CA 1297114

P.C. 7187 NOVEL METHOD OF CHLORINATION Abstract A novel process for chlorinating 2-methoxy- nicotinic acid at the 5-position of the molecule is disclosed. The process involves the use of an alkali metal hypochlorite as the chlorinating agent in a homogeneous aqueous solvent system. The compound so produced, 5-chloro-2-methoxynicotinic acid, is known to be useful as an intermediate leading to various oral hypoglycemic agents of the benzenesulfonylurea class.

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