Method of coating particles

B - Operations – Transporting – 01 – J

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B01J 2/16 (2006.01) A61K 9/50 (2006.01) B01J 13/06 (2006.01)

Patent

CA 2201864

A microparticle comprising an active substance which is a central core made of liquid, gaseous or solid particle of regular or irregular shape, and the method for entrapping said active substance in a coating material which is conformationally distributed on said active substance and has a thickness ranging from the thickness of a monomolecular layer to about 100 µm. These compositions are useful for applications that require protection, prolonged release, taste masking, improved stability, altered handling behavior, altered surface properties including particle wettability, and other desirably altered properties.

On décrit une microparticule comprenant une substance active, laquelle constitue un noyau central composé d'une particule solide, gazeuse ou liquide, de forme régulière ou irrégulière, ainsi qu'un procédé destiné à piéger cette substance active dans un matériau de revêtement, lequel est réparti sur cette substance de manière à suivre la conformation de celle-ci et possède une épaisseur variant de l'épaisseur d'une couche monomoléculaire à environ 100 mu m. Ces compositions sont utiles pour des applications dans lesquelles on souhaite une protection, une libération prolongée, un masquage du goût, une meilleure stabilité, un comportement modifié lors de la manipulation, des propriétés modifiées de surface, notamment l'aptitude au mouillage des particules, ainsi que d'autres propriétés avantageusement modifiées.

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