Method of computer-aided automated diagnostic dna test design

Details Method of computer-aided automated diagnostic dna test design Method of computer-aided automated diagnostic dna test design

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G06F 17/00 (2006.01)

Patent

CA 2263731

The invention encompasses a semi-automatic and/or automatic computer-aided technique for designing comprehensive DNA diagnostic tests for mutations in disease genes through searching for optimized conditions for PCR amplification and for optimal melting behavior in denaturing gradient gels and for optimal distribution in two-dimensional electrophoresis display of the mutational target fragments.

L'invention porte sur une technique automatique et/ou semi-automatique assistée par ordinateur de conception de tests diagnostiques sur l'ADN pour y détecter les mutations de gènes malades en cherchant à obtenir les conditions optimales d'amplification par PCR et le comportement optimal de fusion dans des gels à gradients dénaturants, ainsi que la distribution optimale dans la représentation électrophorétique bidirectionnelle des fragments de la cible mutante.

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