C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 17/00 (2006.01) B01D 15/08 (2006.01) C07K 1/22 (2006.01) C07K 16/06 (2006.01) C12N 9/64 (2006.01) C12N 11/00 (2006.01) G01N 33/531 (2006.01) G01N 33/543 (2006.01) G01N 30/48 (1995.01)
Patent
CA 2158056
A method is disclosed for coupling a ligand within a porous support. The method involves mixing ligand and porous support under conditions sufficient to suppress coupling conditions of the ligand to the porous support while enhancing the relative rate of diffusion, to the rate of reaction, of the ligand into and within the porous support, and then altering the conditions to enhance rapid coupling of the ligand within the porous support. The alteration from diffusion conditions to coupling conditions involves a change in the reaction solution of pH, ionic strength, temperature, or coupling competitor, such that a relatively lower Thiele Modulus during diffusion conditions changes to a relatively higher Thiele Modulus during coupling conditions. Derivatized porous supports produced according to the method are also disclosed. The derivatized porous support has enhanced functional efficiency. Derivatized porous supports prepared from azlactone- functional porous supports are also disclosed.
Milbrath Dean S.
Subramanian Anuradha
Velander William H.
Minnesota Mining And Manufacturing Company
Smart & Biggar
Virginia Tech Intellectual Properties Inc.
Virginia's Center For Innovative Technology
LandOfFree
Method of coupling ligands within porous supports (p.e.... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of coupling ligands within porous supports (p.e...., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of coupling ligands within porous supports (p.e.... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1901836