C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) C07K 14/71 (2006.01) G06F 17/50 (2006.01) G06F 19/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2329132
The present invention relates to a method of designing compounds able to bind to a molecule of the EGF receptor family and to modulate the activity mediated by the receptor molecule based on the 3-D structure coordinates of the EGF receptor crystal of Figure 6.
La présente invention concerne une méthode d'élaboration de composés capables de se lier à une molécule de la famille des récepteurs d'EGF (facteur de croissance des cellules épithéliales) et de moduler l'activité régulée par ladite molécule en fonction des coordonnées de la structure 3D du cristal de récepteur d'EGF de la figure 6.
Burgess Antony Wilks
Elleman Thomas Charles
Epa Vidanagamage Chandana
Garrett Thomas Peter John
Jorissen Robert Nicholas
Biomolecular Research Institute
Commonwealth Scientific And Industrial Research Organisation
Ludwig Institute For Cancer Research
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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