C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) C07K 14/65 (2006.01) C07K 14/71 (2006.01) G06F 17/50 (2006.01) G06F 19/00 (2006.01)
Patent
CA 2311926
The present invention relates to a method of designing compounds able to bind to a molecule of the insulin receptor family and to modulate the activity mediated by the receptor based on the 3-D structure coordinates of a IGF-1 receptor crystal of Figure 1.
Cette invention se rapporte à un procédé permettant de mettre au point des composés capables de se fixer à une molécule de la famille des récepteurs d'insuline et de moduler l'activité induite par le récepteur sur la base des coordonnées de la structure tridimensionnelle d'un cristal du récepteur de l'IGF-1 (facteur de croissance proche de l'insuline-1) représenté par la figure 1.
Bentley John David
Cosgrove Leah Jane
Frenkel Maurice John
Garrett Thomas Peter John
Lawrence Lynne Jean
Commonwealth Scientific And Industrial Research Organisation
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Walter And Eliza Hall Institute Of Medical Research
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