Method of designing sirnas for gene silencing

C - Chemistry – Metallurgy – 40 – B

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C40B 40/06 (2006.01) C07H 21/02 (2006.01) C12Q 1/68 (2006.01) C40B 30/02 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2543954

The present invention provides a method for identifying siRNA target motifs in a transcript using a position-specific score matrix approach. The invention also provides a method for identifying off-target genes of an siRNA using a position-specific score matrix approach. The invention further provides a method for designing siRNAs with higher silencing efficacy and specificity. The invention also provides a library of siRNAs comprising siRNAs with high silencing efficacy and specificity.

L'invention concerne un procédé servant à identifier des motifs cibles ARNsi dans un transcrit au moyen d'une approche à matrice de scores spécifique à la position. L'invention concerne également un procédé servant à identifier des gènes hors cible d'un ARNsi au moyen d'une approche à matrice de scores spécifique à la position. L'invention concerne aussi un procédé servant à désigner des ARNsi présentant une efficacité et une spécificité d'extinction de gènes plus élevées. L'invention concerne en outre une bibliothèque d'ARNsi comprenant des ARNsi présentant une efficacité et une spécificité élevées pour l'extinction de gènes.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method of designing sirnas for gene silencing does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of designing sirnas for gene silencing, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of designing sirnas for gene silencing will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1882996

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.