Method of detecting autoantibodies from patients suffering...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/08 (2006.01) C07K 7/64 (2006.01) C40B 30/04 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2708463

The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.

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