Method of detecting compounds utilizing chemically modified...

Details Method of detecting compounds utilizing chemically modified... Method of detecting compounds utilizing chemically modified...

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 47/48 (2006.01) A61K 51/08 (2006.01) C07K 14/01 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2159716

Disclosed is a protein construct including a chemically modified lambdoid tail protein having a chemically reactive amino acid residue linked to a target molecule. Also disclosed is an infective lambdoid bacteriophage displaying on its outer surface the chemically modified tail protein. In addition, methods of detecting a molecule-of-interest in a solution and methods of detecting cells producing a molecule-of- interest which utilize the infective lambdoid bacteriophage having the chemically modified tail protein are disclosed.

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