Method of detecting human tissue factor active substance

C - Chemistry – Metallurgy – 12 – P

Patent

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530/13, 167/37,

C12P 21/08 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2026666

- 42 - ABSTRACT A method of assaying a human tissue factor active substance in human urine by an immunological technique utilizing an anti-human tissue factor active substance monoclonal antibody. This method is, for example, useful for diagnosis of a kidney disease such as nephritis. The tissue factor active substance derived from human urine is a novel substance. The anti-human tissue factor active substance monoclonal antibody used in the above method and the hybridoma cells producing this antibody are also disclosed.

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