Method of detecting lung disease

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 33/14 (2006.01) A61K 9/12 (2006.01) A61K 9/72 (2006.01) A61K 31/4965 (2006.01) A61K 31/7072 (2006.01) A61P 11/10 (2006.01) C12Q 1/04 (2006.01) C12Q 1/24 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2226892

A method of facilitating the obtaining of a mucus sample from at least one lung of a subject comprises administering to at least one lung of the subject, in an amount effective to hydrate lung mucus secretions and/or stimulate cilia beat frequency therein, uridine 5'-triphosphate, an active analog thereof, or a pharmaceutically acceptable salt of either thereof, and, optionally, concurrently administering to said at least one lung a physiologically acceptable salt in an amount effective to hydrate lung mucus secretions therein. A sputum or mucus sample is then collected from said at least one lung, which sample can then be analyzed for lung disease. Pharmaceutical compositions useful for carrying out the method comprise UTP or a salt thereof, alone or in combination with a physiologically acceptable salt, or a pharmaceutically acceptable salt of either thereof. The composition may be a liquid/liquid suspension composition or a dry powder composition.

Un procédé pour faciliter l'obtention d'un échantillon de mucus d'un ou des deux poumons d'un patient consiste à introduire dans un ou dans les deux poumons de ce patient, en quantité suffisante pour hydrater les sécrétions de mucus pulmonaire et/ou y stimuler la fréquence du battement ciliaire, de l'uridine 5'-triphosphate, un analogue actif de celle-ci ou un sel de ceux-ci acceptable sur le plan pharmaceutique. On peut également administrer de manière concomitante à un ou aux deux poumons un sel acceptable sur le plan physiologique en une quantité suffisante pour hydrater les sécrétions de mucus pulmonaire. Un échantillon de mucus (crachat) est recueilli du ou des poumons et cet échantillon peut être analysé pour diagnostiquer une maladie pulmonaire. Les compositions pharmaceutiques utiles pour mettre en oeuvre ce procédé contiennent de l'UTP ou un sel de celle-ci acceptable sur le plan pharmaceutique, seul ou en combinaison avec un sel acceptable sur le plan physiologique. La composition peut être une suspension liquide/liquide ou une poudre sèche.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method of detecting lung disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of detecting lung disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting lung disease will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1620379

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.