C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2571817
The present invention describes a method for the simultaneous identification of two or more mutations located in the gene encoding Cytochrome P450-2C9. Multiplex detection is accomplished using multiplexed tagged allele specific primer extension (ASPE) and hybridization of such extended primers to a probe, preferably an addressable anti-tagged support.
La présente invention concerne une méthode destinée à l'identification simultanée de deux ou plusieurs mutations situées dans le gène codant pour le cytochrome P450-2C9. Une détection multiplex est réalisée par extension d'amorces spécifiques d'allèles marquées multiplex (ASPE) et par hybridation des amorces ainsi étendues à une sonde, telle que, de préférence, un support non marqué adressable.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Luminex Molecular Diagnostics Inc.
Tm Bioscience Pgx Inc.
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