Method of detecting native probnp with a monoclonal antibody...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/26 (2006.01) C12N 5/20 (2006.01) G01N 33/531 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2522747

The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.

La présente invention concerne des anticorps qui se lient de manière spécifique au proBNP natif, une méthode de détection spécifique du proBNP natif, une méthode de corrélation du niveau du proBNP natif au diagnostic de la défaillance cardiaque, et une trousse de détection du proBNP natif. Elle concerne également une lignée cellulaire hybridome produisant un anticorps dirigé contre le proBNP natif.

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