Method of detecting neurological disease or dysfunction

Details Method of detecting neurological disease or dysfunction Method of detecting neurological disease or dysfunction

C - Chemistry, Metallurgy

12

N

530/13, 167/41,

C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2006332

This invention relates to a method of detecting and diagnosing neurological disease or dysfunction using antibodies against a neuro- logical form of Pancreatic Thread Protein (nPTP). Specifically, this invention is directed to a method of diagnosing Alzheimer'.s Disease, Down's Syndrome, and other neurological diseases or dysfunctions by using monoclonal antibodies and combinations of those monoclonal antibodies to detect nPTP. The invention also relates to the substan- tially pure form of nPTP. The invention additionally relates to a method of diagnosing pancreatic disease using antibodies against Pancreatic Thread Protein.

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