Method of detecting thrombosis by measuring von willebrand...

G - Physics – 01 – N

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G01N 33/573 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2550939

A method of detecting the level of thrombus formation tendency or thrombosis through determining of the quantity of von Willebrand factor splitting enzyme. There is further disclosed a kit for detecting the level of thrombus formation tendency or thrombosis, which kit includes an antibody capable of specific binding to von Willebrand factor splitting enzyme, or a fragment of the antibody. The provided detection method and detection kit excel in convenience, speed and specificity.

L'invention porte sur un procédé qui permet de détecter le niveau de la tendance à la formation de thrombus ou à la thrombose en mesurant la quantité de l'enzyme clivant le facteur de Von Willebrand. L'invention se rapporte également à une trousse qui permet de détecter le niveau de la tendance à la formation de thrombus ou à la thrombose, laquelle trousse comprend un anticorps capable de se lier spécifiquement à l'enzyme clivant le facteur de Von Willebrand, ou un fragment de l'anticorps. Le procédé et la trousse de détection de l'invention possèdent d'excellentes propriétés de commodité, vitesse et spécificité.

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