Method of detecting tumors containing complexes of p53 and...

Details Method of detecting tumors containing complexes of p53 and... Method of detecting tumors containing complexes of p53 and...

G - Physics

01

N

G01N 33/574 (2006.01) G01N 33/543 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2118015

2118015 9321529 PCTABS00027 The present invention relates to the finding that the class of mutant p53 proteins which bind to HSP70 defines a group of mutant p53 proteins which elicit serum autoantibodies. Thus, disclosed is a method of classifying tumor cells for the ability to produce serum p53 autoantibodies in a patient carrying such tumor cells, a method of detecting tumor cells containing a mutant p53 protein capable of forming a complex with a 70 kilodalton heat shock protein (hsp70) in the cells in a patient, a method of distinguishing tumor cells capable of causing more aggressive disease in a patient carrying the tumor cells, and a method of monitoring a patient for the recurrence of disease in a patient previously diagnosed as carrying tumor cells.

Affiliated with

Also associated with

Rating

Method of detecting tumors containing complexes of p53 and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of detecting tumors containing complexes of p53 and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting tumors containing complexes of p53 and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1709616