Method of detection and disease state management for renal...

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G01N 33/573 (2006.01) G01N 33/68 (2006.01) G01N 33/70 (2006.01) G01N 33/88 (2006.01)

Patent

CA 2342897

A method for detecting kidney diseases at the early stage characterized by measuring the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample collected from a subject and comparing the thus measured concentration with the human lipocalin-type prostaglandin D synthase concentration of body fluid samples obtained from healthy subjects; and a method for pathologically controlling kidney diseases characterized by measuring the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample collected from a subject and evaluating the glomerular filtration level of the patient therefrom.

Un procédé de détection des maladies du rein à un stade précoce se caractérise par la mesure de la concentration de prostaglandine D synthase du type lipocaline humaine dans un échantillon de fluide corporel prélevé sur un patient suivie de la comparaison de la concentration ainsi mesurée avec une concentration de prostaglandine D synthase de type lipocaline humaine mesurée dans des échantillons de fluide corporel provenant de patients sains. L'invention concerne également un procédé de surveillance pathologique des maladies du rein qui consiste à mesurer la concentration de prostaglandine D synthase du type lipocaline humaine dans un échantillon de fluide corporel prélevé sur un individu et à évaluer le taux de filtration glomérulaire du patient à partir de cette dernière.

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