Method of detection by enhancement of silver staining

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) G01N 27/447 (2006.01)

Patent

CA 2415494

The present invention relates to a method for amplifying a detection signal by enhancing or promoting the deposition of additional silver in assay detection systems where the formation of a silver spot serves as a reporter for the presence of a target molecule, including biological polymers (e.g., proteins and nucleic acids) and small molecules.

L'invention concerne un procédé d'amplification d'un signal de détection consistant à accroître ou favoriser le dépôt d'argent additionnel dans des systèmes de détection par dosage, dans lesquels la formation d'une tache d'argent sert en tant que marqueur de la présence d'une molécule cible, notamment des polymères biologiques (par exemple des protéines et des acides nucléiques), et des petites molécules.

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