Method of determining renal clearances

G - Physics – 01 – N

Patent

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G01N 33/70 (2006.01)

Patent

CA 2216380

In a method of determining creatinine clearance for detecting and monitoring renal dysfunction, spot samples of urine and blood from a person are obtained. Specific gravity or osmolality and creatinine concentration of the urine sample are measured. Creatinine concentration of plasma of the blood sample is also measured. Creatinine clearance is calculated as a function of the measured urine specific gravity or osmolality, the measured urine creatinine concentration and the measured plasma creatinine concentration.

Dans le cadre d'une méthode pour déterminer la clairance de la créatinine en vue de détecter et de surveiller l'évolution d'une dysfonction rénale, on prélève des échantillons ponctuels d'urine et de sang chez une personne. La densité relative ou l'osmolalité et la concentration de créatinine sont mesurées dans l'échantillon d'urine. On mesure également la concentration de créatinine dans le plasma obtenu à partir de l'échantillon de sang. La clairance de la créatinine est calculée en fonction de la densité relative ou de l'osmolalité mesurée dans l'urine, de la concentration de créatinine mesurée dans l'urine et de la concentration de créatinine mesurée dans le plasma.

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