Method of determining the concentration of pregnanediol...

G - Physics – 01 – N

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G01N 33/74 (2006.01)

Patent

CA 1182044

METHOD OF OVULATION DETECTION AND INDICATOR STRIP FOR USE THEREIN ABSTRACT A method is provided for determining the concentration of pregnanediol glucuronide (PG) in a woman's urine which is characterized by utilization of the reagent 20.alpha.-hydroxy-4-pregnen-3-one (20-.alpha. reagent) in a form in which it reacts with antibodies binding to PG, The method is adaptable to a visual color indication test which can be performed by the woman herself as well as by laboratory analysis. The method can be used to define the period in which conception can occur, to define a post-ovulation safe period in which conception is prevented, and as an early pregnancy indicator. GRANT REFERENCE The research underlying this invention was supported in part by a research contract with the National Institutes of Health (NIH No. 1-HD 9-2841). - 1 -

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