Method of determining the point at which coagulating blood...

G - Physics – 01 – N

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G01N 33/86 (2006.01)

Patent

CA 2605440

The present invention is concerned with a method and apparatus for determining the instant at which coagulating blood forms a clot - the primary function of a clot being to act as a hemostatic plug at the site of a lesion in the circulatory system. The method comprises applying a harmonically time-varying stress and strain of controlled amplitude and frequency to the blood using a rheometer and through the use of the Chambon-Winter Gel Equation, the method is capable of determining the gel point which precedes the clotting time indicated by a thromboelastograph .

La présente invention concerne un procédé et un appareil permettant de déterminer l~instant à partir duquel du sang se coagulant forme un caillot - la fonction principale d~un caillot étant d~agir en tant que thrombus plaquettaire en l~endroit d~une lésion dans l~appareil circulatoire. Ce procédé comprend l~application au sang d~un stress et d~un effort variant dans le temps de manière harmonique ayant une amplitude et une fréquence contrôlées à l~aide d~un rhéomètre et au moyen de l~utilisation de l~équation par gel de Chambon-Winter. Ce procédé peut déterminer le point de gélification qui précède le temps de coagulation qu~affiche le thrombo-élastographe.

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