A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2239709
The invention concerns a method of diagnosing and treating epithelioma, the method being based on the expression of the variant exon v6 of the CD44 gene as the molecular target. In a preferred embodiment, v6-specific antibody molecules, in particular the monoclonal antibody BIWA-1 (VFF-18), are used for this purpose.
L'invention concerne un procédé pour diagnostiquer et traiter les épithéliomes, ce procédé se fondant sur l'expression de la variante exon v6 du gène CD44 comme cible moléculaire. Dans un mode préféré de réalisation, des molécules d'anticorps spécifiques du v6, notamment l'anticorps monoclonal BIWA-1 (VFF-18), sont utilisées à cet effet.
Adolf Gunther
Heider Karl-Heinz
Ostermann Elinborg
Patzelt Erik
Sproll Marlies
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
Forschungszentrum Karlsruhe Gmbh
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