C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2759312
The present invention relates to a method of diagnosing cancer in a subject comprising detecting in the DNA of said subject at least one hypermethylated CpG island associated with said cancer, wherein an elevation in the level of methylation in said CpG island of said subject, relative to the level of methylation in said CpG island of a control subject, is indicative of said CpG island being hypermethylated.
L'invention concerne une méthode pour le diagnostic d'un cancer chez un sujet, qui consiste à détecter dans l'ADN du sujet au moins un îlot CpG hyperméthylé en relation avec ledit cancer, une augmentation du taux de méthylation de l'îlot Cpg chez ledit sujet par rapport au taux de méthylation de l'îlot CpG chez un sujet témoin révélant l'hyperméthylation de l'îlot CpG.
Van Tilborg Annechiena Geertruide
Zwarthoff Ellen Catharina
Erasmus University Medical Center Rotterdam
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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