Method of diagnosing breast cancer using protein markers

G - Physics – 01 – N

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G01N 33/574 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2629013

Disclosed are methods for diagnosing breast cancer in a cell sample by detecting an increase in the levels of expression of protein markers in the cell sample as compared to the levels of expression of the same protein markers in a normal, nonneoplastic breast cell sample, wherein the protein markers are selected from the group consisting of cvtokeratin 19, cathepsin D, ezrin, A-CRABPII, slc9a3r1 and HER- 2.Also disclosed is a device for the diagnosis of breast cancer in a cell sample.

L'invention a pour objet des procédés de diagnostic du cancer du sein dans un échantillon cellulaire par la détection d'une augmentation des niveaux d'expression de marqueurs protéiques dans l'échantillon cellulaire par rapport aux niveaux d'expression des mêmes marqueurs protéiques dans un échantillon de cellules mammaires normales non néoplasiques. L'invention a également pour objet un dispositif pour le diagnostic du cancer dans un échantillon cellulaire.

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