C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 2/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01) C07K 17/00 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01) G01N 33/68 (2006.01) G01N 33/94 (2006.01)
Patent
CA 2393004
The present invention provides methods for diagnosing neurodegenerative disease such as Alzheimer's disease, monitoring the progression and prognosis of the disease and/or monitoring the therapeutic efficacy of any intervention or treatment of the disease comprising measuring the level of .alpha.7 nicotinic acetylcholine receptor protein.
L'invention concerne des procédés pour diagnostiquer une maladie neurodégénérative telle que la maladie d'Alzheimer, surveiller l'évolution de la maladie et pronostiquer cette maladie et/ou surveiller l'efficacité thérapeutique de n'importe quelle intervention ou n'importe quel traitement de la maladie, y compris pour mesurer le taux de la protéine réceptrice d'acétylcholine nicotinique .alpha.7.
Lee Daniel H. S.
Plata-Salaman Carlos R.
Reitz Allen B.
Wang Hoau-Yan
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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