Method of diagnosis of a predisposition to develop...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2560838

The present invention refers to a method of diagnosis of a predisposition to develop thrombotic disease, to test systems and their use for the diagnosis of a predisposition to develop thrombotic disease, to a P2X1 promoter variant and its use for screening for an anti-thrombotic agent, and to methods for identifying an individual that can be prophylactically or therapeutically treated with an anti-thrombotic agent, or for adapting a therapeutic or prophylactic dose of an anti-thrombotic agent.

La présente invention concerne une technique et un diagnostic de prédisposition à développer une maladie thrombotique, des systèmes de test et l'utilisation du diagnostic de prédisposition à développer une maladie thrombotique, un variant de promoteur P2X1 et l'utilisation de celui-ci pour rechercher un agent antithrombotique et, des techniques d'identification d'une personne qui peut être traitée de manière prophylactique ou thérapeutique avec un agent entier thrombotique ainsi que des techniques permettant d'adapter un dosage thérapeutique ou prophylactique d'un agent antithrombotique.

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