Method of diagnosis of prostate cancer

A - Human Necessities – 01 – N

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A01N 1/00 (2006.01) C12N 5/08 (2006.01) G01N 1/30 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2341897

The present invention relates to structures involved in the secretory processes of reproductive tissues, including the prostatic secretory processes, and their protein products which may be used as tools for diagnosing reproductive pathology including prostate disease. The present invention also relates to reagents, such as antibodies, other ligands and oligonucleotides, for detecting these structures or their contents and to methods of diagnosing prostate pathology, including prostate cancer and prostatitis. The invention further relates to an improved tissue and cell fixation process for the detection of secretory structures in reproductive tissue. The fixation process is useful for the diagnosis of prostate, testes and renal cancer.

L'invention porte sur des structures participant au processus sécrétoire de tissus reproducteurs, dont celui de la prostate, et sur leurs produits protéiques qui peuvent servir d'outils diagnostiques des pathologies de la reproduction dont les maladies de la prostate. L'invention porte également sur des réactifs tels que des anticorps et autres ligands et oligonucléotides de détection de ces structures ou de leur contenu et sur des procédés de diagnostic des pathologies de la prostate y compris le cancer de la prostate et les prostatites. L'invention porte en outre sur un procédé amélioré de fixation de tissus et de cellules servant à la détection des processus sécrétoires dans des tissus reproducteur s'avérant utile pour le diagnostic des cancers de la prostate, des testicules, et des reins.

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