Method of diagnosis of type 2 diabetes and early onset thereof

Details Method of diagnosis of type 2 diabetes and early onset thereof Method of diagnosis of type 2 diabetes and early onset thereof

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2516371

The invention pertains to the field of human genetics and relates to new methods of diagnosis and therapy of type 2 diabetes (T2D), early onset type 2 diabetes and Maturity-Onset Diabetes of the Young (MODY) in a human subject, based on the identification of the A185G variation located at exon 2 of the tieg2 gene as well as the G-1534C, 54a, 304a, +659 C>T (Thr220Met) and +1039 G>T (Ala347Ser) variations.

L'invention a trait au domaine de la génétique humaine et concerne de nouvelles méthodes de diagnostic et de traitement du diabète de type 2 (T2D), du diabète de type 2 à début précoce et du diabète du type de la maturité chez un sujet jeune (MODY) chez un sujet humain, ces méthodes reposant sur l'identification de la variation A185G située au niveau de l'exon 2 du gène tieg2, ainsi que les variations G-1534C, 54a, 304a, +659 C>T (Thr220Met) et +1039 G>T (Ala347Ser).

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