Method of dissolving antifungal agent, and compositions with...

A - Human Necessities – 61 – K

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A61K 9/08 (2006.01) A61K 31/137 (2006.01) A61K 31/5375 (2006.01) A61K 47/10 (2006.01) A61P 31/10 (2006.01)

Patent

CA 2753638

The invention provides a pharmaceutical composition which comprises: -an antifungal agent from the class of the allylamines or the morpholines, at a concentration of at least 5 %; -a ternary solvent system comprising water; at least one branched or straight chain C2-C8 alkanol; at least one glycol; the total amount of water representing more than 30 % (w/w) of the composition. This composition is intended for application to the nail for the treatment of onychomycoses.

La présente invention concerne une composition pharmaceutique qui comprend : - un agent antifongique de la classe des allylamines ou des morpholines, à une concentration d'au moins 5 %; - un système de solvant ternaire comprenant de l'eau; au moins un alcanol en C2-C8 à chaîne linéaire ou ramifiée; au moins un glycol; la quantité totale d'eau représentant plus de 30 % (p/p) de la composition. Cette composition est destinée à être appliquée sur les ongles pour le traitement d'onychomycoses.

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