Method of efficiently establishing induced pluripotent stem...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/10 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2697621

Provided is a method of improving the efficiency of establishment of induced pluripotent stem cells, comprising culturing somatic cells under hypoxic conditions in the step of nuclear reprogramming thereof.

L'invention porte sur un procédé d'amélioration de l'efficacité de l'établissement de cellules souches pluripotentes induites, comprenant la culture de cellules somatiques dans des conditions hypoxiques lorsquelles sont à l'étape de reprogrammation nucléaire.

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