Method of encapsulating bio material in bead polymers

C - Chemistry – Metallurgy – 12 – N

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195/34.1, 195/35

C12N 1/00 (2006.01)

Patent

CA 1230566

ABSTRACT OF THE DISCLOSURE Spherical polymer particles may be produced by dispers- ing water-soluble monomers or polymers in a hydrophobic solvent, such as toluene or chloroform. These solvents, however, have a dewatering effect on sensitive biomaterials if these are simulta- neously enclosed in the polymer particles. The present invention shows that it is possible to enclose sensitive biomaterials selected from plant cells, animal cells, bacteria, algae and fungi, in spherical polymer particles with retained viability and growth capacity if a suitable combination of polymer and dispers- ing medium is used. The polymer is selected from agar, agarose and fibrinogen. The dispersing medium is selected from paraffin oil, soybean oil, liquid silicone, phthalic acid dibutyl ester and tri-n-butyl phosphate.

440377

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