Method of encapsulating hydrophobic organic molecules in...

B - Operations – Transporting – 01 – J

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B01J 13/16 (2006.01) A01N 25/28 (2006.01) A01N 31/02 (2006.01) A23L 1/00 (2006.01) A61K 8/11 (2006.01) A61Q 5/10 (2006.01) A61Q 13/00 (2006.01) A61Q 17/04 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2487352

It is known to encapsulate various materials in polyurea microcapsules, but obtaining satisfactory microcapsules incorporating alcoholic materials has proven difficult. A process has now been found where polyurea microcapsules are formed by interfacial polymerization between an aqueous phase and a water- immiscible phase, and properties, particularly the solubility parameters, of the water~ immiscible phase are closely matched to corresponding properties of the polyurea. Microcapsules prepared by this process have improved stability, mechanical strength and controlled release properties.

Les procédés pour encapsuler divers matériaux dans des microcapsules de polyurée sont connus, mais il s'est avéré difficile d'obtenir des microcapsules contenant des matériaux alcoolisés satisfaisantes. Cette invention concerne un procédé selon lequel des microcapsules de polyurée sont produites par polymérisation interfaciale entre une phase aqueuse et une phase non miscible à l'eau, certaines propriétés, notamment les paramètres de solubilité, de la phase non miscible à l'eau étant étroitement adaptées à des propriétés correspondantes de la polyurée. La présente invention concerne également des microcapsules préparées selon ce procédé, qui présentent une meilleure stabilité, une meilleure résistance mécanique et de meilleures propriétés de libération contrôlée.

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