Method of enhancing bioavailability of fexofenadine and its...

Details Method of enhancing bioavailability of fexofenadine and its... Method of enhancing bioavailability of fexofenadine and its...

A - Human Necessities

61

K

A61K 31/75 (2006.01) A61K 31/445 (2006.01) A61K 31/525 (2006.01) A61K 31/77 (2006.01) A61K 47/42 (2006.01)

Patent

CA 2301267

The present invention relates to a method of enhancing the bioavailability of a piperidinoalkanol antihistamine in a patient which comprises co-administering to said patient an effective antihistaminic amount of said piperidinoalkanol and an effective p-glycoprotein inhibiting amount of a p-glycoprotein inhibitor.

L'invention concerne un procédé permettant de renforcer la biodisponibilité d'un antihistaminique d'alcanol de pipéridine chez un patient. Selon ce procédé, il s'agit de co-administrer au patient concerné une quantité antihistaminique efficace dudit alcanol de pipéridine et un inhibiteur de p-glycoprotéine, en quantité suffisante pour inhiber la p-glycoprotéine.

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