Method of enhancing delivery of a therapeutic nucleic acid

Details Method of enhancing delivery of a therapeutic nucleic acid Method of enhancing delivery of a therapeutic nucleic acid

A - Human Necessities

61

K

A61K 48/00 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2435443

The invention provides methods and compositions for increasing the delivery of nucleic acids into a host by administering a nucleic acid encoding a therapeutic nucleic acid along with an agent that modulates Kupffer cell function in the host.

La présente invention concerne des procédés et des compositions permettant d'augmenter la remise d'acides nucléiques chez un hôte par administration d'un acide nucléique codant un acide nucléique thérapeutique en même temps qu'un agent qui module la fonction des cellules de Kupffer chez l'hôte.

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