Method of enhancing iontophoretic delivery of a peptide

A - Human Necessities – 61 – N

Patent

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A61N 1/30 (2006.01)

Patent

CA 2700309

The present invention provides methods for the administration of a peptide to a body surface of the patient comprising treating said body surface by microporation and iontophoretically administering the peptide to the body surface. The present invention also encompasses a method of transdermally administering a peptide to the skin of a patient comprising treating the skin with microporation and iontophoretically administering said peptide to the skin. In one embodiment, the body surface or skin is microporated using one or more microneedles.

L'invention concerne des procédés pour l'administration d'un peptide à une surface corporelle d'un patient comprenant le traitement de ladite surface corporelle par microporation et administration iontophorétique du peptide à la surface corporelle. La présente invention concerne également un procédé d'administration transdermique d'un peptide à la peau d'un patient comprenant le traitement de la peau par microporation et administration iontophorétique dudit peptide à la peau. Dans un mode de réalisation, la surface corporelle ou la peau est microporée à l'aide d'une ou de plusieurs micro-aiguilles.

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