Method of enhancing memory or correcting memory deficiency...

Details Method of enhancing memory or correcting memory deficiency... Method of enhancing memory or correcting memory deficiency...

A - Human Necessities

61

K

167/208

A61K 31/435 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/505 (2006.01) C07D 453/02 (2006.01)

Patent

CA 1320448

66197-206 AHR-492 METHOD OF ENHANCING MEMORY OR CORRECTING MEMORY DEFICIENCY WITH ARYLAMIDO(AND ARYLTHIOAMIDO) AZABICYCLOALKANES ABSTRACT OF THE DISCLOSURE A pharmaceutical composition for improving memory or correcting memory deficiency is disclosed, utilizing com- pounds having the formula: Image wherein n1,n2,n3,and n4 = 0to3;R1,R2,R3,andR4 = H,loweralkylor phenyl; R5 = H or loweralkyl; X = 0 or S; Ar = phenyl, substituted phenyl, pyridinyl, furanyl, thienyl, methoxy-lH-benzotriazolyl, indolinyl, methoxy- indolinyl, methoxypyrimidinyl, amino-methoxypyrimadinyl, 1,3- benzodioxolyl, or naphthalenyl; the optical isomers; and the pharmaceutically acceptable acid addition salts, hydrates and alcoholates thereof. The dosage effective for this use is from about 10 to 1000 nanograms/kg.

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