Method of enhancing the delivery of growth factors

A - Human Necessities – 61 – K

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A61K 38/18 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2269075

The diffusion of a growth factor into and around the brain is enhanced by co- infusion with the growth factor receptor. This allows the factor to exert its biological influence over a broader range of tissue. In specific embodiments, BDNF diffusion is enhanced by co-administration of soluble trkB receptor.

On améliore la diffusion dans le cerveau et autour du cerveau d'un facteur de croissance en administrant conjointement le récepteur du facteur de croissance. Ceci permet au facteur d'exercer son influence biologique sur une plus grande étendue du tissu. Selon des réalisations spécifiques, on améliore la diffusion du BDNF (facteur neurotrophique dérivé du cerveau) en administrant conjointement un récepteur trkB soluble.

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