C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61P 3/04 (2006.01) C12N 15/09 (2006.01) C12Q 1/02 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2534309
In the evaluation of a compound such as screening of a remedy for obesity, use is made of the expression level of Slc25a10 gene or its protein in a test tissue or a test cell or the properties of the gene or protein for the evaluation. To examine obesity, the examination is made on the basis of the expression amount of the Slc25a10 gene, a polymorphism in the gene, etc.
Selon l'invention, dans l'évaluation d'un composé, et notamment dans le criblage d'un médicament contre l'obésité, on utilise le niveau d'expression du gène Slc25a10 ou de sa protéine dans un tissu de test ou une cellule de test ou les propriétés de ce gène ou de cette protéine en vue de l'évaluation. Pour déterminer une obésité, on réalise un examen sur la base du niveau d'expression du gène Slc25a10, d'un polymorphisme dans ce gène, etc.
Araki Hiromitsu
Itadani Hiraku
Kotani Hidehito
Miki Satomi
Mizuarai Shinji
Banyu Pharmaceutical Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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