Method of evaluating compound efficacious in treating obesity

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 48/00 (2006.01) A61P 3/04 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2532150

In examining obesity or leanness, the examination is made based on the expression level of LCE gene or its protein in a test tissue or a test cell, a polymorphism in the gene or the like. In evaluating a compound such as screening a remedy for obesity or leanness, the evaluation is made with the use of the characteristics of the LCE gene or its protein.

L'examen de l'obésité ou de la maigreur s'effectue en fonction du niveau d'expression du gène LCE ou de sa protéine dans un tissu ou une cellule à analyser, d'un polymorphisme dans le gène ou similaire. L'évaluation d'un composé, tel que le criblage d'un remède contre l'obésité ou la maigreur, s'effectue à l'aide des caractéristiques du gène LCE ou de sa protéine.

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